Mainstream Tcap and Vcap were performed to assess normalized phase 2 (Sn2 T, Sn2 V) and phase 3 slopes (Sn3 T, Sn3 V) in the time and volumetric domains. Lung injury was induced by iv lipopolysaccharide, whole lung lavage and injurious ventilation in anesthetized, mechanically ventilated rabbits ( n = 26). We compared the diagnostic value of indices derived from Tcap and Vcap following ventilation to perfusion ratio ( ) mismatch subsequent to experimentally induced acute respiratory distress syndrome (ARDS), and alveolar recruitment by elevating the positive end-expiratory pressure (PEEP). Whereas time capnography (Tcap) is routinely displayed during mechanical ventilation, the volumetric representation (Vcap) is seldom used. 4EA-7442 RSRM Laboratory, Department of Clinical Physiology, Sleep and Exercise, Grenoble University Hospital, University of Grenoble, Grenoble, France.3Department of Anesthesiology and Intensive Therapy, University of Szeged, Szeged, Hungary.

2Unit for Anesthesiological Investigations, Department of Anesthesiology, Pharmacology and Intensive Care, University of Geneva, Geneva, Switzerland.1Department of Medical Physics and Informatics, University of Szeged, Szeged, Hungary.Fodor 2† Barna Babik 3 André Dos Santos Rocha 2 Sam Bayat 4 Ferenc Peták 1* Walid Habre 2

Shunt vs dead space oxygen